An ageing population is becoming one of the most significant social transformations of the 21st century. Russia has set an ambitious goal of joining the club of 80+ countries, to increase life expectancy to 80 years by 2030. Only 20% of our health is dependent on our genes; everything else consists of biological factors that we can influence. At the same time, not everything and not always depends on the state alone. Preventive care, timely diagnosis, adopting gold standards of treatment, healthy lifestyle, responsible attitude to ones own health are key elements of preventive medicine, which not only make it possible to achieve the goal of 80+, but also significantly reduce the governments expenditures on the treatment of diseases which can and need to be prevented. Today we have to talk about the quality of life, not just its expectancy. Only an increase in the duration of a quality life can affect economic growth. For the first time the state programme features such indicator as an increase in a quality life expectancy. What are the advantages and disadvantages of the modern approaches of preventive medicine? Which government programmes are aimed at achieving the 80+ goal? What does science know about preventing age-related changes?