The trauma caused by the pandemic of 2020 has highlighted the global challenge of addressing problems in national healthcare systems, many of which were found to be lacking in terms of being able to adequately respond. Meanwhile, people with acute and chronic conditions were forced to go without proper and timely treatment. Governments the world over now need to take stock of the situation in light of the events of the past year. It is vital to consolidate efforts to develop effective steps aimed at modernizing national healthcare systems. These should be based on principles of resilience, safety, and flexibility. And while it is important the ensure that the resources are in place to defeat COVID-19, healthcare systems must also be structured so that people have rapid and uninterrupted access to high-quality and full medical care. Today, international solidarity is key to improving humanitys resilience to epidemics and other disasters. No one person can ever be completely safe, and not everyone is out of danger yet. What are the main features of an effective and resilient healthcare system today, and what might be the optimum models for the future? What initiatives set up during the pandemic warrant further development? How could a global information system informing the general public of potential risks be set up, and why is such a system necessary? What Russian crisis response models could be adapted and applied in other countries?