Creative industries are increasingly regarded as an important driver of economic growth which allows many countries and companies to infiltrate global value chains and simultaneously solve an array of social and cultural problems. Drawing on the UN-based approach, creative industries are essentially creating, producing and distributing goods and services grounded in creative and intellectual capital, where the economic value of the end product is connected to and corresponds to its intellectual (or cultural) value. Why are creative industries significant in the process of creating a global value chain, developing regions and preserving heritage? Which of the creative industry sectors are, in our opinion, most promising in terms of creating a global value chain, developing regions and preserving heritage? What are the main development trends in the creative industry, nationally and worldwide, as regards the creation of a global value chain and both regional and cultural development?