Natural and man-made disasters cause significant economic and social damage to the economies of the Asia-Pacific Region, disrupting business and reducing the Far Easts investment appeal. In light of this, it is essential to combine our efforts, increase resilience to risk and invest in disaster risk reduction. The Sendai Framework for Disaster Risk Reduction for 20152030 takes significant steps in this direction. Its implementation will ensure stable socioeconomic growth in the Far East. What global and Russian trends can be observed in the impact of disasters on the economy? How does the risk of disaster affect development of entrepreneurial activity in the Asia-Pacific Region? How can the Sendai Framework for Disaster Risk Reduction help ensure business safety and increase the investment appeal of the Far East? What is the role of civil society in increasing national, regional and municipal resilience in the face of disaster?