Providing support for enterprise and stimulating investment are the two chief areas of work for regional development institutes. On the one hand, the challenges are well understood, but on the other, by no means all regions are responding to them with equal success. How is the work of development institutes organized at the regional level? How transparent are their activities and what are the main indicators of their effectiveness? Who evaluates the work of these organizations and how? What motivates their leaders and to what extent are these leaders personally accountable? How feasible is it to introduce uniform performance standards to the work of regional development institutes?